Jang-Hern Lee Selected Research

GABA-A Receptor Antagonists

11/2010	An increase in spinal dehydroepiandrosterone sulfate (DHEAS) enhances NMDA-induced pain via phosphorylation of the NR1 subunit in mice: involvement of the sigma-1 receptor.
6/2009	Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABA receptors.

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Jang-Hern Lee Research Topics

Disease

40	Hyperalgesia 01/2022 - 08/2004
37	Pain (Aches) 01/2022 - 02/2001
27	Neuralgia (Stump Neuralgia) 01/2022 - 08/2004
15	Inflammation (Inflammations) 09/2018 - 12/2004
8	Hypersensitivity (Allergy) 01/2022 - 08/2011
5	Peripheral Nerve Injuries 01/2022 - 01/2017
5	Peripheral Nervous System Diseases (PNS Diseases) 11/2019 - 08/2004
5	Thrombosis (Thrombus) 01/2014 - 10/2008
5	Ischemia 01/2012 - 10/2008
5	Arthritis (Polyarthritis) 10/2008 - 02/2001
4	Chronic Pain 12/2016 - 08/2004
3	Spinal Cord Injuries (Spinal Cord Injury) 07/2015 - 07/2010
3	Hypoxia (Hypoxemia) 01/2014 - 10/2008
3	Edema (Dropsy) 03/2008 - 02/2001
2	Hypotension (Low Blood Pressure) 05/2016 - 03/2009
2	Acidosis 03/2011 - 08/2010
2	Rheumatoid Arthritis 10/2008 - 02/2001
2	Wounds and Injuries (Trauma) 06/2006 - 06/2006
1	Pleurisy (Pleuritis) 09/2018
1	Migraine Disorders (Migraine) 02/2018
1	Acute Pain 01/2018

Drug/Important Bio-Agent (IBA)

13	Sigma-1 ReceptorIBA 01/2022 - 12/2008
12	Bee Venoms (Bee Venom)IBA 09/2018 - 02/2001
11	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2021 - 06/2006
9	N-Methylaspartate (NMDA)IBA 12/2021 - 02/2010
8	N- (2- (3,4- Dichlorphenyl)ethyl)- N,N',N'- trimethyl- 1,2- ethandiaminIBA 01/2022 - 06/2006
8	CarrageenanIBA 09/2018 - 03/2008
7	2- (4- morpholino)ethyl- 1- phenylcyclohexane- 1- carboxylateIBA 01/2022 - 11/2008
7	Formaldehyde (Formol)FDA Link 01/2018 - 03/2003
6	Analgesics (Analgesic Drugs)IBA 12/2021 - 02/2001
6	Adrenergic Receptors (Adrenergic Receptor)IBA 05/2016 - 11/2011
5	EnzymesIBA 10/2019 - 01/2019
5	Serine (L-Serine)FDA Link 01/2019 - 10/2015
5	Clonidine (ST 155)FDA LinkGeneric 05/2016 - 08/2008
4	Dehydroepiandrosterone (DHEA)IBA 01/2022 - 06/2009
4	p38 Mitogen-Activated Protein KinasesIBA 10/2019 - 09/2013
4	CytochromesIBA 10/2019 - 01/2019
4	NeurosteroidsIBA 10/2019 - 06/2009
3	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 11/2019 - 12/2016
3	Ketoconazole (Nizoral)FDA LinkGeneric 10/2019 - 01/2019
3	SB 203580IBA 10/2019 - 04/2014
3	Proteins (Proteins, Gene)FDA Link 08/2019 - 01/2014
3	7-nitroindazoleIBA 01/2019 - 08/2011
3	Capsaicin (Zostrix)FDA Link 02/2018 - 07/2008
3	Purinergic P2Y1 ReceptorsIBA 01/2017 - 01/2014
3	Adenosine Triphosphate (ATP)IBA 01/2014 - 08/2010
3	ZymosanIBA 10/2008 - 07/2005
3	Freund's AdjuvantIBA 10/2008 - 02/2001
3	CatecholaminesIBA 10/2007 - 09/2005
2	CalciumIBA 01/2022 - 08/2011
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2021 - 01/2017
2	Protein Isoforms (Isoforms)IBA 11/2019 - 06/2010
2	serine racemaseIBA 01/2019 - 01/2017
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2019 - 01/2017
2	fluorocitrateIBA 01/2019 - 12/2016
2	Mitogen-Activated Protein KinasesIBA 01/2017 - 04/2014
2	Connexin 43 (Connexin43)IBA 01/2017 - 12/2016
2	2- iodo- N(6)- methyl- (N)- methanocarba- 2'- deoxyadenosine- 3',5'- bisphosphateIBA 01/2017 - 04/2014
2	NADPH Oxidase 2IBA 12/2016 - 08/2013
2	CarbenoxoloneIBA 12/2016 - 07/2010
2	acetovanillone (apocynin)IBA 12/2016 - 08/2013
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 05/2016 - 03/2016
2	Therapeutic UsesIBA 01/2013 - 02/2001
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2012 - 10/2008
2	Evans Blue (Blue, Evans)FDA Link 01/2012 - 10/2008
2	Pharmaceutical PreparationsIBA 03/2011 - 08/2008
2	BicucullineIBA 11/2010 - 06/2009
2	GABA-A Receptor AntagonistsIBA 11/2010 - 06/2009
2	Ala(2)-MePhe(4)-Gly(5)- Enkephalin (DAGO)IBA 02/2010 - 08/2008
2	CollagenIBA 06/2006 - 06/2006
2	Opioid Analgesics (Opioids)IBA 01/2006 - 08/2004
1	Progesterone FDA LinkGeneric 01/2022
1	2- ((1H- benzo(d)(1,2,3)triazol- 5- ylamino)methyl)- 4,6- dichlorophenolIBA 11/2019
1	Messenger RNA (mRNA)IBA 08/2019
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2019
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2019
1	7-chlorokynurenic acidIBA 01/2019
1	Aminoglutethimide (Cytadren)FDA Link 01/2019
1	LigandsIBA 01/2019
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	Protein Kinase CIBA 01/2019
1	Dizocilpine Maleate (Dizocilpine)IBA 01/2019
1	trilostane FDA Link 01/2019
1	linsidomineIBA 01/2019
1	resiniferatoxinIBA 02/2018
1	Nitroglycerin (Dynamite)FDA LinkGeneric 02/2018
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2018
1	Aromatase (CYP19)IBA 01/2018
1	serine O-sulfateIBA 01/2017
1	InterleukinsIBA 01/2017
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 01/2017
1	PotassiumIBA 01/2017
1	D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA 01/2017

Therapy/Procedure

9	Acupuncture Points (Acupuncture Point) 09/2018 - 02/2001
5	Therapeutics 09/2018 - 02/2001
5	Spinal Injections 12/2016 - 11/2008
3	Electroacupuncture 03/2008 - 01/2006
2	Complementary Therapies (Alternative Medicine) 09/2018 - 02/2001
2	Injections 01/2014 - 02/2001
2	East Asian Traditional Medicine (Oriental Medicine) 08/2004 - 02/2001